Резюме

Вальпроат натрия оказывает выраженное антиишемическое действие в остром периоде черепно-мозговой травмы. Золпидем эффективнее при локальной ишемии мозга.

Study of neuroprotectic properties of gaba-mimetic drugs was carried on model of craniocerebral trauma. It is obvious, that high antiischemic activity possesses valproate natrii on local ischemii brain and craniocerebral trauma. Zolpidem preferably increasing antiischemic activity on model of local ischemii brain. It can be expected that applying valproate natrii and zolpidem were revealed of importance in the pharmacological treatment of secondary brain injury.